Selected Publications: Sepsis

1.            Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, et al. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. The Lancet. 2020;395(10219):200-11.

2.            Cummings MJ, Lutwama JJ, Owor N, Tomoiaga AS, Ross JE, Muwanga M, et al. Unsupervised Classification of the Host Response Identifies Dominant Pathobiological Signatures of Sepsis in Sub-Saharan Africa. Am J Respir Crit Care Med. 2025;211(3):357-69.

3.            Cummings MJ, Bakamutumaho B, Jain K, Price A, Owor N, Kayiwa J, et al. Development of a Novel Clinicomolecular Risk Index to Enhance Mortality Prediction and Immunological Stratification of Adults Hospitalized with Sepsis in Sub-Saharan Africa: A Pilot Study from Uganda. Am J Trop Med Hyg. 2023;108(3):619-26.

4.            Cummings MJ, Bakamutumaho B, Price A, Owor N, Kayiwa J, Namulondo J, et al. HIV infection drives pro-inflammatory immunothrombotic pathway activation and organ dysfunction among adults with sepsis in Uganda. AIDS. 2023;37(2):233-45.

5.            Cummings MJ, Lutwama JJ, Owor N, Tomoiaga AS, Ross JE, Muwanga M, et al. Host Response Stratification in Malarial and Non-malarial Sepsis: A Prospective, Multicenter Analysis From Uganda. Crit Care Med. 2025.

6.            Cummings MJ, Jacob ST. Equitable endotyping is essential to achieve a global standard of precise, effective, and locally-relevant sepsis care. EBioMedicine. 2022;86:104348.

7.            Bakamutumaho B, Lutwama JJ, Owor N, Kayiwa J, Kiconco J, Haumba M, et al. Epidemiology, Clinical Characteristics, and Mortality of Hospitalized Patients with Severe COVID-19 in Uganda, 2020-2021. Ann Am Thorac Soc. 2022;19(12):2100-3.

8.            Cummings MJ, Bakamutumaho B, Lutwama JJ, Owor N, Che X, Astorkia M, et al. COVID-19 immune signatures in Uganda persist in HIV co-infection and diverge by pandemic phase. Nature Communications. 2024;15(1):1475.